HTML5 and the latest standard web technologies have finally driven the developer community towards a cross-platform app and game deployment scenario. Still, there are some challenges that have to be solved in order to smooth the experience of getting a final product to the increasing number of markets, from fragmented platforms to performance issues or ways to access specific features of each target in a cross-platform way. This article provides an overview of the most common challenges and some tips and technologies available today in order to overcome them.